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MYP_142080
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Basic Information
Secretin
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
27 amino acids
C130H219N43O42
Standard
Sequence
HSDGTFTSELSRLRDSARLQRLLQGLV
Physicochemical Analysis
3056.39 Da
9.45
0.85
0.60
0.0316
-0.46
0.70
-0.20
63.74
101.11
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1415.66
-17.44
52.0
44.0
105.0
215.0
2.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273245 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
Secretin
9606;32630
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Diagnostic
PaperPubMed-linked source references: PMID:15780490; PMID:20641871; PMID:25619391 PMID15780490;20641871;25619391 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15780490/
RECORD: Rec_0288108 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Secretin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory Feeding regulator
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Secretin (Ovis aries): PMID 2034821 PMID2034821 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2034821/
RECORD: Rec_0303373 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Secretin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory Feeding regulator
secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Secretin (Bos taurus): PMID 7250377 PMID7250377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7250377/
RECORD: Rec_0370675 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Glucagon
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2034821 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2034821/
RECORD: Rec_0371437 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]; Bos taurus [Animal]; Ovis aries [Animal]; Cavia porcellus [Animal]
9823, 9913, 9940, 10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
bicarbonate secretion
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