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MYP_142007
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
52 amino acids
C216H332N62O91S
Standard
Sequence
DDDGQSESQAVNGKTGASEAVPSEGKGELEHSQQEEDGEEAMAGPPQGLFPG
Physicochemical Analysis
5285.37 Da
4.05
-11.12
-11.40
-0.2139
-1.20
0.32
-0.11
69.62
35.77
0.0192
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2457.80
-36.22
77.0
82.0
178.0
370.0
6.0
57.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032008 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0046664 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Chromogranin/secretogranin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Ser32 Phosphoserine
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
Evidence URLhttps://www.uniprot.org/uniprotkb/CMGA_RAT/entry
RECORD: Rec_0266387 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Pancreastatin
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
8:Phosphoserine; 32:Phosphoserine
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
inhibits catecholamine release from chromaffin cells
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PMID29166604 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29166604/
RECORD: Rec_0395918 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Pancreastatin
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
8:Phosphoserine; 32:Phosphoserine
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PMID29166604 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29166604/