Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC456H715N133O127S10

DescriptionStandard

        MTICRKRFEKLYSEKHNFSTIFEKAKYGTKKNNPARSKEQYAVFNWWEACIKLSGQCKNRCGEKEFKMSYCARPTTLCCLRHCDRIE
    

Molecular Weight10413.02 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)9.61

Net Charge (pH 7.4) 9.13

Charge Density (pH 7.0) 0.1104

GRAVY Index-0.87

Hydrophobic Moment 0.54

Boman Index-0.26

Instability Index47.08

Aliphatic Index 44.94

Aromaticity 0.1264

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4303.37

LogP -41.99

H-bond Donors 161.0

H-bond Acceptors 149.0

Rotatable Bonds 356.0

Heavy Atoms 726.0

Ring Count 17.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146066 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus maritimus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence