Peptide Database

Peptide NameCecropin C

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC137H234N44O36

DescriptionStandard

        GWLKKLGKRLERIGQHTRDASIQVIGI
    

Molecular Weight3073.60 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.1425

GRAVY Index-0.41

Hydrophobic Moment 0.92

Boman Index-0.11

Instability Index12.68

Aliphatic Index 115.56

Aromaticity 0.0370

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1329.39

LogP -11.36

H-bond Donors 48.0

H-bond Acceptors 41.0

Rotatable Bonds 109.0

Heavy Atoms 217.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333949 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila serrata [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)