Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC205H308N58O62S2

DescriptionStandard

        QLNFTPNWGTGKRDAADFADPYSFLYRLIQAEARKMSGCSN
    

Molecular Weight4641.12 Da

Isoelectric Point (pI)8.15

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0183

GRAVY Index-0.65

Hydrophobic Moment 0.67

Boman Index-0.09

Instability Index11.33

Aliphatic Index 50.24

Aromaticity 0.1463

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1969.53

LogP -21.76

H-bond Donors 69.0

H-bond Acceptors 65.0

Rotatable Bonds 149.0

Heavy Atoms 327.0

Ring Count 9.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133855 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0149983 VERIFIED: NO

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyAKH/HRTH/RPCH

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsThr10 Amidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone Metabolic

RECORD: Rec_0424579 VERIFIED: YES

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyAdipokinetic prohormone type

Tax ID7004

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Disulfide39-39

Other Mods10:Threonine amide

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour