Peptide Database

Peptide NameU-poneritoxin(01)-Om2a (U-PONTX(01)-Om2a) (Pilosulin-like peptide 2) (PLP2) (Poneratoxin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC377H591N93O110S6

DescriptionStandard

        MKPSGITFAFLVVFMMAIMYNSVQAAAIADADADAEAKAFADAFAEAGWGSIFKTVGKMIAKAAVKAAPEAISAMASQNEK
    

Molecular Weight8378.67 Da

Isoelectric Point (pI)5.14

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.73

Charge Density (pH 7.0) -0.0184

GRAVY Index0.49

Hydrophobic Moment 0.69

Boman Index0.27

Instability Index20.08

Aliphatic Index 80.00

Aromaticity 0.0988

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3204.27

LogP -28.31

H-bond Donors 108.0

H-bond Acceptors 115.0

Rotatable Bonds 277.0

Heavy Atoms 586.0

Ring Count 11.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192193 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0311525 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic

TargetSaccharomyces cerevisiae

RECORD: Rec_0425272 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic

TargetEscherichia coli