Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC397H625N105O134S12

DescriptionStandard

        MKTFTAAVIVAVALTICIEGNAAFPFTAVEDVEEEKSTDDPAATQEETSVETWMMPFDIGENRDASPVRCRHCCDCCLLSGCGICCQ
    

Molecular Weight9397.61 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-10.47

Net Charge (pH 7.4) -10.89

Charge Density (pH 7.0) -0.1204

GRAVY Index0.14

Hydrophobic Moment 0.35

Boman Index0.10

Instability Index56.39

Aliphatic Index 70.69

Aromaticity 0.0575

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3787.59

LogP -41.93

H-bond Donors 137.0

H-bond Acceptors 137.0

Rotatable Bonds 303.0

Heavy Atoms 648.0

Ring Count 11.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046906 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis aureus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal