Peptide Database

Peptide Namebeta-Defensin, DEFB10

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC169H258N46O51S6

DescriptionStandard

        ERCEKVRGICKTFCDDVEYDYYCIKWRSQCCV
    

Molecular Weight3942.52 Da

Isoelectric Point (pI)6.34

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.49

Charge Density (pH 7.0) -0.0069

GRAVY Index-0.53

Hydrophobic Moment 0.58

Boman Index-0.22

Instability Index35.24

Aliphatic Index 51.56

Aromaticity 0.1562

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1613.01

LogP -13.66

H-bond Donors 64.0

H-bond Acceptors 57.0

Rotatable Bonds 130.0

Heavy Atoms 272.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353985 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-30; 10-23; 14-31

Bio-Activity Profile

Function

Antimicrobial