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MYP_141786
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C119H186N30O22
Standard
Sequence
KWKLFKKIGPGKFLHSAKKF
Physicochemical Analysis
2388.94 Da
10.78
6.84
6.58
0.3420
-0.61
0.52
-0.07
-10.75
63.50
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
854.27
-2.15
30.0
30.0
83.0
171.0
7.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071486 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
K-562
>100 μM
IC50
PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0131249 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
100 μM
Hemolysis
PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0155877 VERIFIED: YES
Provenance & Taxonomy
Ceropin-Magainin hybrid [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
75 μM
IC50
PaperPubMed PMID: 10675500 PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0158425 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10675500/ PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0194254 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Toxic Hemolytic
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
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