Peptide Database

Peptide NameGaegurin-5 (1-13)[V8A,A9L,K11H,V12L], PTP-7b

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC71H112N16O15

DescriptionStandard

        FLGALFKALSHLL
    

Molecular Weight1429.75 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0651

GRAVY Index1.53

Hydrophobic Moment 0.47

Boman Index0.56

Instability Index-8.86

Aliphatic Index 165.38

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 487.45

LogP -0.31

H-bond Donors 17.0

H-bond Acceptors 17.0

Rotatable Bonds 46.0

Heavy Atoms 102.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413079 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGaegurin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 43300

Activity4 μM

MethodMIC

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