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MYP_141784
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Basic Information
Gaegurin-5 (1-13)[V8A,A9L,K11H,V12L], PTP-7b
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C71H112N16O15
Standard
Sequence
FLGALFKALSHLL
Physicochemical Analysis
1429.75 Da
8.76
0.85
0.59
0.0651
1.53
0.47
0.56
-8.86
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.45
-0.31
17.0
17.0
46.0
102.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Normal breast cells MCF-10a
56 μM
IC50
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0093852 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25404
64 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0094555 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 8
PaperPubMed PMID: 22934601 PMID22934601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22934601/
RECORD: Rec_0118835 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID22934601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22934601/
RECORD: Rec_0137764 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
4 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
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