Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length480 amino acids

Chemical FormulaC2332H3721N649O729S12

DescriptionStandard

        MQQQRVNADLETAKITEPQRVENARLTAEAAEKAARDRRISEEIAATEAKRQRMENERLAEQERQRVEGTKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVVLSLREAAELHNSFLAAQEQLSAIATISASGSVAAMIALGIYQTKVGESSERPPGWNVSPKFVGSISLSAMGLPATESLASQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAAQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAETRPILAPPGSTPATLQHTGEMIIKPVITPTILPLPQLYARDFHDDIIWFPADSGLEPVYVYLNSPYGKTTAKGKYSGRDFNPDKAGGPIKNLDWKEIKIRGEGVDEVKLHTRRFGELEDNKLMIERLEKILTNKLTATDIDKRFYTHEIRELERYRMLGIPDDVNDKSVWNDAHTATLEDFKINEKTQPLYTSEAEDAYIKAELKNSLGSK
    

Molecular Weight52898.18 Da

Isoelectric Point (pI)5.65

Net Charge (pH 7.0)-6.90

Net Charge (pH 7.4) -7.60

Charge Density (pH 7.0) -0.0144

GRAVY Index-0.45

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index40.19

Aliphatic Index 80.19

Aromaticity 0.0667

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 53985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0251917 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia pseudotuberculosis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)