Peptide Database

Peptide NameAlpha-defensin 1 (Cryptdin-1) (Defensin-related cryptdin peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC444H723N129O146S8

DescriptionStandard

        MKKLVLLFALVLLGFQVQADSIQNTDEETKTEEQPGEEDQAVSVSFGDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
    

Molecular Weight10460.79 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-3.45

Net Charge (pH 7.4) -3.83

Charge Density (pH 7.0) -0.0370

GRAVY Index-0.48

Hydrophobic Moment 0.59

Boman Index-0.13

Instability Index41.20

Aliphatic Index 76.45

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4502.46

LogP -50.57

H-bond Donors 162.0

H-bond Acceptors 152.0

Rotatable Bonds 361.0

Heavy Atoms 727.0

Ring Count 8.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079447 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found