Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length727 amino acids

Chemical FormulaC3409H5335N929O1065S17

DescriptionStandard

        MSTVLYIHPPHGCYVFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYNHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGTQFISVTGSGSQPYSLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEILSSLGAAVGRVIASLGATATAGTAGPMVAAASAILFSPAAGGGSDRVPGRDLNAMFALNAQLLAGPDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFAESDANKIMIDRLEKILNGEMQPTDTDKRFYTHEIRELERYRNLGIKDGIIPDNQGDVWNNTHTATLEDYKINERNEPLYTPDAIQAAEEQAKREYL
    

Molecular Weight76918.52 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-28.09

Net Charge (pH 7.4) -29.28

Charge Density (pH 7.0) -0.0386

GRAVY Index-0.27

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index34.92

Aliphatic Index 78.58

Aromaticity 0.0646

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 76905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217322 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0375556 VERIFIED: YES