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MYP_141681
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Basic Information
NRC-123
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C136H210N38O31
Standard
Sequence
GWKDWFRKAKKVGKTVGGLALNHYL
Physicochemical Analysis
2873.36 Da
10.30
4.84
4.58
0.1937
-0.54
0.82
-0.02
23.46
78.00
0.1600
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1134.83
-6.71
41.0
37.0
96.0
205.0
7.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062875 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>256 μg/mL
Hemolysis
PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0070348 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HL-60 (50% Cell death=16 μg/ml)
PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0073015 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0256853 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21729875/ PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0303200 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 32.0%, E 0.0%, T 52.0%, C 16.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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