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MYP_141666
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Basic Information
Puroindoline-A (34-46)[F1R,P2K,V3r,T4W,G13R]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C108H146N34O14
Standard
Sequence
RKRWWRWWKWWKR
Physicochemical Analysis
2144.53 Da
12.00
6.76
6.55
0.5198
-2.70
0.76
-0.75
147.51
0.00
0.4615
33000.00
33000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
832.92
1.00
35.0
21.0
65.0
156.0
12.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0343453 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep red blood cells
500 μg/mL
Hemolysis
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0344696 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
16 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0362987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
16 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0377501 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes: No hemolysis up tp 500 μg/ml
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
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