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MYP_141642
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C23H35N5O8
Standard
Sequence
TQVY
Physicochemical Analysis
509.55 Da
5.18
-0.60
-0.79
-0.1507
-0.33
0.41
0.11
-49.05
72.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
234.17
-1.90
8.0
8.0
14.0
36.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0283548 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
ACE inhibitory peptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive Enzyme-inhibitory Neuropeptide
ace
18.2 μM
IC50
PaperAntihypertensive peptides from animal products, marine organisms, and plants | Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities | Isolation and characterization of peptides with antihypertensive activity in foodstuffs | PubMed PMID 17392118 | PubMed PMID 10784421 PMID17392118;10784421 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17392118/
RECORD: Rec_0297677 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0356336 VERIFIED: NO
Provenance & Taxonomy
Oryza sativa [Plant]
ACE-inhibitory peptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
18.2 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0366415 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
ACE-inhibitory peptide
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
18.2 μM
IC50
PaperAntihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. PMID17392118 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17392118/
RECORD: Rec_0390769 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
40 mmHg
SBP decrease
PaperAntihypertensive Properties of Plant Protein Derived Peptides PMID10784421 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784421/
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