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MYP_141625
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
8 amino acids
C43H68N12O12S
Standard
Sequence
RDMPIQAF
Physicochemical Analysis
977.14 Da
5.84
-0.24
-0.44
-0.0299
-0.26
0.23
-0.04
63.67
61.25
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
400.52
-2.64
13.0
13.0
30.0
68.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000336 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
197.46 μM
IC50
RECORD: Rec_0057296 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
209 μM
IC50
RECORD: Rec_0065415 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
209 μM
IC50
PaperAntihypertensive Effect of the Peptides Derived from Casein by an Extracellular Proteinase from Lactobacillus helveticus CP790 | Yamamoto, N. et al. | DOI: 10.3168/jds.S0022-0302(94)77026-0 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0110395 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
noncanonical stereochemical modification [Modified]
Oxidation at M3
Bio-Activity Profile
-
PaperPeptide profiling of bovine kefir reveals 236 unique peptides released from caseins during its production by starter culture or kefir grains PMID25613046 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25613046/
RECORD: Rec_0140610 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperProduction of angiotensin-I-converting-enzyme-inhibitory peptides in fermented milks started by Lactobacillus delbrueckii subsp. bulgaricus SS1 and Lactococcus lactis subsp. cremoris FT4 PMID10966406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10966406/
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