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MYP_141611
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Basic Information
CPF-C1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
17 amino acids
C77H132N22O20
Standard
Sequence
GFGSLLGKALRLGANVL
Physicochemical Analysis
1686.01 Da
11.00
1.76
1.55
0.1035
0.90
0.61
0.34
10.75
143.53
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
680.16
-5.89
24.0
22.0
57.0
119.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197417 VERIFIED: YES
Provenance & Taxonomy
Tetraploid frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 2760
128 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0202755 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0203199 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 725
8 μg/mL
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0210717 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 850
16 μg/mL
MIC
PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
RECORD: Rec_0218634 VERIFIED: YES
Provenance & Taxonomy
Tetraploid frog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcuss aureus 936
32 μg/mL
MIC
PaperNovel antimicrobial peptide CPF-C1 analogs with superior stabilities and activities against multidrug-resistant bacteria. Chem Biol Drug Des. 2017 Nov;90(5):690-702. doi: 10.1111/cbdd.12988. PMID: 28371431. PMID28371431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28371431/
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