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MYP_141604
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Basic Information
Antimicrobial peptide ToAP2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
79 amino acids
C447H709N107O111S4
Standard
Sequence
MQFKKQLLVIFFAYFLVVNESEAFFGTLFKLGSKLIPGVMKLFSKKKERSLMKRELKNLYDPYQRSVEMERLLKELPLY
Physicochemical Analysis
9486.32 Da
9.82
6.51
6.26
0.0824
-0.07
0.66
0.02
25.90
99.87
0.1519
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3556.72
-16.68
123.0
122.0
329.0
669.0
15.0
83.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046066 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Chemotactic Cytotoxic Hemolytic
Candida albicans
PMID27917162;29848960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
RECORD: Rec_0081459 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Chemotactic Cytotoxic Hemolytic
M. massiliense (Gram-positive/Gram-negative)
PMID27917162;29848960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
RECORD: Rec_0169130 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
[PubMed ID: 29848960] M.massiliense [PubMed ID: 27917162] Candida spp.
PMID27917162;29848960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
RECORD: Rec_0170517 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Chemotactic Cytotoxic Hemolytic
Cryptococcus neoformans
PMID27917162;29848960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
RECORD: Rec_0349161 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Chemotactic Cytotoxic Hemolytic
Candida spp.
PMID27917162;29848960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
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