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MYP_141564
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Basic Information
Leucosulfakinin-II
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
10 amino acids
C53H73N15O19S
Standard
Sequence
ESDDYGHMRF
Physicochemical Analysis
1256.30 Da
4.54
-2.07
-2.30
-0.2075
-1.60
0.16
-0.31
12.23
0.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
568.16
-5.63
20.0
19.0
40.0
88.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012342 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Gastrin/cholecystokinin
6978
Structure & Mods
linear peptide [Linear]
modified natural L-amino-acid peptide [Modified]
Pyroglutamate
Amidation
N-terminal pyroglutamate; Tyr5 sulfation; C-terminal amidation
Bio-Activity Profile
Neuropeptide Sulfakinin Myotropic
cockroach hindgut muscle
Myotropic contraction assay
PMID2615921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2615921/
RECORD: Rec_0024898 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0144391 VERIFIED: YES
Provenance & Taxonomy
Rhyparobia maderae [Animal]
Leucosulfakinin
36963
Structure & Mods
linear peptide [Linear]
modified natural L-amino-acid peptide [Modified]
Pyroglutamate
Amidation
N-terminal pyroglutamate; Tyr5 sulfation; C-terminal amidation
Bio-Activity Profile
Neuropeptide Sulfakinin Myotropic
cockroach hindgut muscle
Myotropic contraction assay
Mammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Leucosulfakinin-2 (Rhyparobia maderae): PMID 3778455 PMID3778455 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3778455/
RECORD: Rec_0172646 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Leucosulfakinin
6978
Structure & Mods
linear peptide [Linear]
modified natural L-amino-acid peptide [Modified]
Pyroglutamate
Amidation
N-terminal pyroglutamate; Tyr5 sulfation; C-terminal amidation
Bio-Activity Profile
Neuropeptide Sulfakinin Myotropic
cockroach hindgut muscle
Myotropic contraction assay
Mammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Leucosulfakinin-II (Periplaneta americana): PMID 2615921 PMID2615921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2615921/
RECORD: Rec_0420128 VERIFIED: YES
Provenance & Taxonomy
Rhyparobia maderae [Animal]
Gastrin/cholecystokinin
36963
Structure & Mods
linear peptide [Linear]
modified natural L-amino-acid peptide [Modified]
Pyroglutamate
Amidation
N-terminal pyroglutamate; Tyr5 sulfation; C-terminal amidation
Bio-Activity Profile
Neuropeptide Sulfakinin Myotropic
cockroach hindgut muscle
Myotropic contraction assay
PMID3778455 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3778455/