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MYP_141498
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Basic Information
P8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C62H109N23O12
Standard
Sequence
AARIILRPRFR
Physicochemical Analysis
1368.68 Da
12.00
3.80
3.61
0.3451
-0.04
0.46
-0.34
54.76
124.55
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
593.13
-3.77
23.0
16.0
44.0
97.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. pullorum 7913
32 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0078488 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium C77-31
32 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0086025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans cgmcc2.2086
128 μM
MIC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0090836 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells [10% hemolysis at >128 microM]
128 μM
Hemolysis
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0091201 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli 25922
32 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
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