Peptide Database

Peptide NameBrevinin-1Pk

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC222H359N59O69S2

DescriptionStandard

        NAEEERRDEPDETDVEVEKRFLPIIAGVAAKVFPKIFCTISKKC
    

Molecular Weight5022.71 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.0509

GRAVY Index-0.45

Hydrophobic Moment 0.63

Boman Index-0.13

Instability Index59.99

Aliphatic Index 79.77

Aromaticity 0.0682

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2080.83

LogP -17.54

H-bond Donors 72.0

H-bond Acceptors 69.0

Rotatable Bonds 170.0

Heavy Atoms 352.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197380 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Tax ID8404

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0263913 VERIFIED: NO