Peptide Database

Peptide NameHPIV3 F HRC derived peptide(449-484)[L451N]

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Influenza virus

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC179H297N51O62

DescriptionStandard

        VANDPIDISIELNKAKSDLEESKEWIRRSNQKLDSI
    

Molecular Weight4155.58 Da

Isoelectric Point (pI)4.77

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -2.48

Charge Density (pH 7.0) -0.0626

GRAVY Index-0.87

Hydrophobic Moment 0.66

Boman Index-0.23

Instability Index67.75

Aliphatic Index 100.28

Aromaticity 0.0278

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1888.61

LogP -20.09

H-bond Donors 64.0

H-bond Acceptors 60.0

Rotatable Bonds 147.0

Heavy Atoms 292.0

Ring Count 3.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391080 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetinhibition of fusion in HeLa cells

Activity0.75 μM

MethodIC50

RECORD: Rec_0399746 VERIFIED: YES