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MYP_141450
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Basic Information
L4R
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
8 amino acids
C68H89N21O9
Standard
Sequence
WWWRRRIW
Physicochemical Analysis
1344.57 Da
12.00
2.76
2.56
0.3450
-1.57
0.30
-0.37
151.95
48.75
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.88
1.52
22.0
12.0
37.0
98.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045178 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human RBCs
200 μM
Hemolysis
PMID28731688 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
RECORD: Rec_0047946 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
K-pneumoniae ATCC 13883
>25 μM
MIC
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0052981 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
25 μM
MIC
PMID28731688 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
RECORD: Rec_0054936 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus USA300 LAC
12.5 μM
MIC
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0159821 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
human RBC: not hemo.lytic
>200 μM
HC50
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy. PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
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