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MYP_141449
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Basic Information
Angiotensin I-converting enzyme inhibitory peptide 2
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
9 amino acids
C38H68N12O12
Standard
Sequence
AIGVGAIER
Physicochemical Analysis
885.02 Da
6.05
-0.20
-0.39
-0.0224
0.89
0.32
0.31
38.84
141.11
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
395.32
-3.54
14.0
12.0
29.0
62.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177218 VERIFIED: YES
Provenance & Taxonomy
Schistocerca gregaria [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
14.43 ± 0.02 μg/mL
IC50
RECORD: Rec_0187154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
Alpha-glucosidase
14.73
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0247215 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Metabolic Syndrome Pancreatic lipase inhibitory
Pancreatic lipase
56.47
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0252149 VERIFIED: YES
Provenance & Taxonomy
Tenebrio molitor [Animal]
7067.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperZieli¨½ska E., Baraniak B., Kara? M.. Identification of antioxidant and anti-inflammatory peptides obtained by simulated gastrointestinal digestion of three edible insects species (Gryllodes sigillatus, Tenebrio molitor, Schistocerca gragaria). Int. J. Food Sci. Technol., 53, 2542-2551,.
RECORD: Rec_0343124 VERIFIED: YES
Provenance & Taxonomy
Schistocerca gregaria [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
lipase
49.95 ± 0.2 μg/mL
IC50
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