‹ ›
MYP_141420
← PREVIOUS NEXT → BACK
Basic Information
Atrial natriuretic peptide (ANP)
Binding / Molecular interaction ▸ Binding activity
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C127H205N45O39S3
Standard
Sequence
SLRRSSCFGGRMDRIGAQSGLGCNSFRY
Physicochemical Analysis
3082.46 Da
10.66
3.44
3.20
0.1229
-0.50
0.60
-0.20
82.88
45.36
0.1071
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1403.38
-20.26
55.0
46.0
104.0
214.0
3.0
29.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0369017 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Cardiovascular
PMID1826098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1826098/
RECORD: Rec_0371014 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Atrial natriuretic peptide
9913
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
7-23
6:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Myotropic Receptor modulation ACE inhibitory
Experimental: 22 minutes; /1320 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Atrial natriuretic peptide (Bos taurus): PMID 2942845 PMID2942845 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2942845/
RECORD: Rec_0381646 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0397128 VERIFIED: YES
Provenance & Taxonomy
Equus caballus [Animal]
Natriuretic peptide
9796
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Cardiovascular
PMID3007908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3007908/
RECORD: Rec_0399312 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7月23日
Bio-Activity Profile
Natriuretic Vasodilator Cardiovascular
Natriuretic peptide receptor A
Clinical/Human: 2 min
Evidence URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396233/
FIRST PREV 1 ... 4 5 6 7 NEXT LAST
Showing 5 records on this page · Page 6 of 7