Peptide Database

Peptide NameColicin pyosin nuclease family protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length297 amino acids

Chemical FormulaC1382H2211N387O431S10

DescriptionStandard

        MVPGRDISSMMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSPADALGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFDDIILVFPPESGLKPLYVMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSSRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKTELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK
    

Molecular Weight31464.32 Da

Isoelectric Point (pI)6.22

Net Charge (pH 7.0)-2.03

Net Charge (pH 7.4) -2.57

Charge Density (pH 7.0) -0.0069

GRAVY Index-0.29

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index40.82

Aliphatic Index 78.18

Aromaticity 0.0539

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196520 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)