Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC898H1431N247O275S20

DescriptionStandard

        MKTFSVAVVAAVLLALICLQESSALPLSEVEDVEVPVMDDNGAAVYEEMPVDSWQMPYTNRHKRSPKHCRQEKSEELTRVTCTRVKARNQLEQFSPPEMKTFSVAVVAAVLLALICLQESSALPLSEVEDGGVPVMDDNGAAVYEEMPVDSWQMPYTNIYKRRPQRCRFCCNCCPGIQGCGVCCRF
    

Molecular Weight20728.76 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-6.40

Net Charge (pH 7.4) -6.94

Charge Density (pH 7.0) -0.0344

GRAVY Index-0.09

Hydrophobic Moment 0.49

Boman Index0.01

Instability Index72.58

Aliphatic Index 80.11

Aromaticity 0.0645

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 19200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8331.83

LogP -95.86

H-bond Donors 294.0

H-bond Acceptors 291.0

Rotatable Bonds 675.0

Heavy Atoms 1440.0

Ring Count 29.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102731 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu flavidus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal