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MYP_141297
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Basic Information
Gaegurin-5 (1-13)[F6W,V8A,A9L,K11H,V12L], LL-1b
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C73H113N17O15
Standard
Sequence
FLGALWKALSHLL
Physicochemical Analysis
1468.78 Da
8.76
0.85
0.59
0.0651
1.25
0.46
0.53
20.92
165.38
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
503.24
0.17
18.0
17.0
46.0
105.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234941 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 15% Hemolysis=30 μM
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0237803 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium
64 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0241218 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Normal breast cells MCF-10a
49 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0291884 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
31 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0335035 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10420
4 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
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