MYP_141249
Lysocin E
Antimicrobial
Standard
12 amino acids
C67H104N20O19
Standard
TRSGFLREQWIT
1493.67 Da
9.26
0.40
0.21
0.0334
-0.70
0.13
-0.17
77.88
65.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
664.09
-6.17
25.0
20.0
48.0
106.0
3.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0053417
VERIFIED: YES
Provenance & Taxonomy
Lysobacter species [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
R2, R7, Q9, and W10 are D-amino acids (XXD). The amide proton of F5 is methylated (XXM). The amide of T1 is acylated (XXL). The sidechain OH of T1 forms an ester bond with the carboxyl group of T12 (XXJ), leading to a macrolactone
Bio-Activity Profile
Antimicrobial
lab-generated vancomycin-resistant Staphylococcus aureus
8 μg/mL
MIC
RECORD: Rec_0081941
VERIFIED: YES
Provenance & Taxonomy
Lysobacter species [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
R2, R7, Q9, and W10 are D-amino acids (XXD). The amide proton of F5 is methylated (XXM). The amide of T1 is acylated (XXL). The sidechain OH of T1 forms an ester bond with the carboxyl group of T12 (XXJ), leading to a macrolactone
Bio-Activity Profile
Antimicrobial
Bacillus spp
2 μg/mL
MIC
RECORD: Rec_0191444
VERIFIED: YES
Provenance & Taxonomy
Lysobacter species [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
R2, R7, Q9, and W10 are D-amino acids (XXD). The amide proton of F5 is methylated (XXM). The amide of T1 is acylated (XXL). The sidechain OH of T1 forms an ester bond with the carboxyl group of T12 (XXJ), leading to a macrolactone
Bio-Activity Profile
Antimicrobial
Mycobacterium spp
8 μg/mL
MIC
RECORD: Rec_0299703
VERIFIED: YES
Provenance & Taxonomy
Lysobacter species [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
R2, R7, Q9, and W10 are D-amino acids (XXD). The amide proton of F5 is methylated (XXM). The amide of T1 is acylated (XXL). The sidechain OH of T1 forms an ester bond with the carboxyl group of T12 (XXJ), leading to a macrolactone
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus MRSA
4 μg/mL
MIC
RECORD: Rec_0336052
VERIFIED: YES
Provenance & Taxonomy
Lysobacter species [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
R2, R7, Q9, and W10 are D-amino acids (XXD). The amide proton of F5 is methylated (XXM). The amide of T1 is acylated (XXL). The sidechain OH of T1 forms an ester bond with the carboxyl group of T12 (XXJ), leading to a macrolactone
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes
1 μg/mL
MIC