Peptide Database

Peptide NameBradykinin-potentiating peptide 11d

Function Ontology

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Ion channel modulation

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC51H81N15O13

DescriptionStandard

        QGRPPGPPIPP
    

Molecular Weight1112.28 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0691

GRAVY Index-1.26

Hydrophobic Moment 0.28

Boman Index-0.03

Instability Index76.51

Aliphatic Index 35.45

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 406.57

LogP -3.88

H-bond Donors 10.0

H-bond Acceptors 14.0

Rotatable Bonds 24.0

Heavy Atoms 79.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024765 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

FamilyBradykinin-potentiating peptide 11d

Tax ID8724

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Targetangiotensin-converting enzyme

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0033587 VERIFIED: YES

Provenance & Taxonomy

OrganismGloydius halys [Animal]

FamilyBradykinin-potentiating peptide

Tax ID8714

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0298346 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

FamilyBradykinin-potentiating peptide 11d

Tax ID8724

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0346994 VERIFIED: YES

Provenance & Taxonomy

OrganismGloydius halys [Animal]

FamilyBradykinin-potentiating peptide

Tax ID8714

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Targetangiotensin-converting enzyme

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour