MYP_141241
ANF (Arg101-Tyr126) (Atrial natriuretic factor )
Neurological / Signaling
▸
Neuropeptide activity
▸
Neuropeptide
Standard
26 amino acids
C118H189N43O36S3
Standard
RRSSCFGGRMDRIGAQSGLGCNSFRY
2882.22 Da
10.66
3.74
3.51
0.1439
-0.65
0.54
-0.25
81.07
33.85
0.1154
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1324.95
-19.27
52.0
43.0
97.0
200.0
3.0
27.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0145168
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21
Radioiodinated peptide at Tyr
Bio-Activity Profile
Natriuretic
IC50
Male Sprague-Dawley rats plasma (Dose i/p injected), in vivo; 17.1 s
RECORD: Rec_0166130
VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal] [Animal]; Homo sapiens [Animal]
9940;9606
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
5-21
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0389852
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21
Bio-Activity Profile
Natriuretic
Radioimmunoassay
Human plasma, in vivo; 270 s