Peptide Database

Peptide NameDefensin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC392H632N104O111S12

DescriptionStandard

        MAGKGVGTPLSALFLLVLLVVTIGMMEVQVAEGRMCKTPSAKFKGYCVSSTNCKNVCRTEGFPTGSCDFHITSRKCYCYKPCP
    

Molecular Weight8962.62 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)5.51

Net Charge (pH 7.4) 5.10

Charge Density (pH 7.0) 0.0664

GRAVY Index0.22

Hydrophobic Moment 0.47

Boman Index0.12

Instability Index19.79

Aliphatic Index 70.36

Aromaticity 0.0843

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3404.24

LogP -34.94

H-bond Donors 127.0

H-bond Acceptors 130.0

Rotatable Bonds 291.0

Heavy Atoms 619.0

Ring Count 13.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144241 VERIFIED: NO

Provenance & Taxonomy

OrganismPinus sylvestris [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence