Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC574H931N163O190S9

DescriptionStandard

        MKPLLLALSMLVLLPQVIPAYSGEKKCWNKSGHCRKQCKDGEAVRETCKNLQVCCVPSNEDRRVPTTSSTPLNDSSPGTMDDILTVRFTTDYFEVSSKKDVVEESESGQGTQTSLPNVHHSS
    

Molecular Weight13444.10 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.77

Charge Density (pH 7.0) -0.0105

GRAVY Index-0.52

Hydrophobic Moment 0.63

Boman Index-0.09

Instability Index50.04

Aliphatic Index 70.16

Aromaticity 0.0410

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5696.22

LogP -70.27

H-bond Donors 201.0

H-bond Acceptors 201.0

Rotatable Bonds 447.0

Heavy Atoms 936.0

Ring Count 17.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102012 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyBeta-defensin; Defensin

Tax ID37293

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic