Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC362H571N95O101S11

DescriptionStandard

        MKTVFFLFALLFFVGPAKNAFFSEKCSKLNGRCTSYCQKNEELIALCHMTLKCCAMVQPCGRIKGNDSAEDMAA
    

Molecular Weight8222.70 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.14

Charge Density (pH 7.0) 0.0341

GRAVY Index0.19

Hydrophobic Moment 0.43

Boman Index0.10

Instability Index26.42

Aliphatic Index 70.00

Aromaticity 0.1081

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3148.84

LogP -29.01

H-bond Donors 114.0

H-bond Acceptors 116.0

Rotatable Bonds 276.0

Heavy Atoms 569.0

Ring Count 11.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154459 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin