Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length579 amino acids

Chemical FormulaC2667H4235N733O848S12

DescriptionStandard

        LSAGSLPETVPVHSRIQDDVHDGAQFISVTGSSSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFTRAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGLYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGESAENVVMIDRLEKILKGELQPTDTDKRFYTHEIRELERYRAVGVLDGVSPDDDGVTWNNTHTATLEDYKLSSDRSLLYTPEALKAGDE
    

Molecular Weight60520.34 Da

Isoelectric Point (pI)5.00

Net Charge (pH 7.0)-21.18

Net Charge (pH 7.4) -22.10

Charge Density (pH 7.0) -0.0366

GRAVY Index-0.21

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index31.66

Aliphatic Index 81.14

Aromaticity 0.0535

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079889 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence