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MYP_141120
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Basic Information
Nisin H
Antimicrobial
Antiviral
Standard
34 amino acids
C151H251N41O47S7
Standard
Sequence
FTSISMCTPGCKTGALMTCNYKTATCHCSIKVSK
Physicochemical Analysis
3617.31 Da
9.02
3.79
3.46
0.1116
0.19
0.29
0.09
18.05
48.82
0.0588
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1413.21
-19.04
56.0
59.0
118.0
246.0
4.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020428 VERIFIED: YES
Provenance & Taxonomy
Streptococcus hyointestinalis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Staphylococcus aureus ATCC 29213 MSSA or MRSA
0.19-0.78 μM
MIC
PaperNisin H Is a New Nisin Variant Produced by the Gut-Derived Strain Streptococcus hyointestinalis DPC6484.
RECORD: Rec_0157561 VERIFIED: YES
Provenance & Taxonomy
Streptococcus hyointestinalis [Bacterium]
Bacteriocin
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0254176 VERIFIED: YES
Provenance & Taxonomy
Streptococcus hyointestinalis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
anti-VRE, and Bacillus subtilis 168
0.1 μM
MIC
PaperNisin H Is a New Nisin Variant Produced by the Gut-Derived Strain Streptococcus hyointestinalis DPC6484.
RECORD: Rec_0342981 VERIFIED: YES
Provenance & Taxonomy
Streptococcus hyointestinalis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Enterococcus faecalis ATCC 29212 or 51299 VRE
1.56 μM
MIC
PaperNisin H Is a New Nisin Variant Produced by the Gut-Derived Strain Streptococcus hyointestinalis DPC6484.
RECORD: Rec_0402615 VERIFIED: YES
Provenance & Taxonomy
Streptococcus hyointestinalis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
E. faecium ATCC 35667 or 700221 VRE
0.39 μM
MIC
PaperNisin H Is a New Nisin Variant Produced by the Gut-Derived Strain Streptococcus hyointestinalis DPC6484.