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MYP_141112
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Basic Information
Pilosulin P2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C103H184N32O22
Standard
Sequence
GLLSKFGRLARKLARVIPKV
Physicochemical Analysis
2222.76 Da
12.00
5.76
5.55
0.2879
0.30
1.03
-0.05
-0.43
136.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
891.42
-5.63
33.0
28.0
77.0
157.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0129173 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
RECORD: Rec_0153285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
10 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15639237/ PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
RECORD: Rec_0163986 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella Typhimurium ATCC 14028
4-8 μg/mL
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
RECORD: Rec_0181454 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0210313 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853 or resistant strains
2-4 μM
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
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