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MYP_141112
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Basic Information
Pilosulin P2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C103H184N32O22
Standard
Sequence
GLLSKFGRLARKLARVIPKV
Physicochemical Analysis
2222.76 Da
12.00
5.76
5.55
0.2879
0.30
1.03
-0.05
-0.43
136.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
891.42
-5.63
33.0
28.0
77.0
157.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001868 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
10 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/18568863/ PMID18568863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18568863/
RECORD: Rec_0021128 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
15% hemolysis at 10 uM and 40% hemolysis at 100 uM
>100 μM
HC50
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
RECORD: Rec_0032977 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. maltophila O-16451 or I-10717
1-1.5 μM
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
RECORD: Rec_0063837 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
C. freundii I-11090
2 μM
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
RECORD: Rec_0116030 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Micrococcus luteus
1 μM
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
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