Peptide Database

Peptide NameCoccinin

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Antiviral

Antiviral ▸ Anti-HIV

Plant bioactivity ▸ Plant defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC50H79N13O20

DescriptionStandard

        KQTENLADTY
    

Molecular Weight1182.24 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.1238

GRAVY Index-1.50

Hydrophobic Moment 0.45

Boman Index-0.29

Instability Index28.38

Aliphatic Index 49.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 572.71

LogP -6.85

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 39.0

Heavy Atoms 83.0

Ring Count 1.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421607 VERIFIED: YES

Provenance & Taxonomy

OrganismPhaseolus coccineus [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anticancer Antiviral Cytotoxic Hemolytic Anti-HIV

TargetHuman promyelocytic leukemia HL-60

Activity30 μM

MethodIC50

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