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MYP_141085
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Basic Information
Coccinin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiviral
Antiviral ▸ Anti-HIV
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C50H79N13O20
Standard
Sequence
KQTENLADTY
Physicochemical Analysis
1182.24 Da
4.37
-1.24
-1.45
-0.1238
-1.50
0.45
-0.29
28.38
49.00
0.1000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
572.71
-6.85
19.0
19.0
39.0
83.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008789 VERIFIED: YES
Provenance & Taxonomy
Phaseolus coccineus [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiviral Cytotoxic Hemolytic Anti-HIV
HIV-1
41 μM
IC50
PMID15572193;25815330 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15572193/
RECORD: Rec_0012040 VERIFIED: NO
Provenance & Taxonomy
Phaseolus coccineus [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Fungicide Plant Defense Antiviral Anti-HIV Non-hemolytic Non-ribosomal
Botrytis cinerea, C.comatus, Fusarium oxysporum, P.piricola
Qualitative functional evidence
PMID15572193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15572193/; https://www.uniprot.org/uniprotkb/P84785/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0021043 VERIFIED: YES
Provenance & Taxonomy
Phaseolus coccineus [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiviral Cytotoxic Hemolytic Anti-HIV
Physalospora piricola
89±4 μM
IC50
PMID15572193;25815330 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15572193/
RECORD: Rec_0035015 VERIFIED: YES
Provenance & Taxonomy
Phaseolus coccineus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Rhizoctomia solani
134±2 μM
IC50
PaperPubMed PMID: 15572193 PMID15572193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15572193/
RECORD: Rec_0091096 VERIFIED: YES
Provenance & Taxonomy
Phaseolus coccineus [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiviral Cytotoxic Hemolytic Anti-HIV
Botrytis cinerea
109±5 μM
IC50
PMID15572193;25815330 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15572193/
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