‹ ›
MYP_141044
← PREVIOUS NEXT → BACK
Basic Information
CA-MA
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C120H190N30O22
Standard
Sequence
KWKLFKKIGIGKFLHSAKKF
Physicochemical Analysis
2404.98 Da
10.78
6.84
6.58
0.3420
-0.31
0.63
-0.01
-14.99
83.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
863.06
-1.61
31.0
30.0
86.0
172.0
6.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0083872 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME / cecropin-magainin hybrid
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
K-562
65.0 μM
IC50 / MTT-MTS assay
PaperPMID 10675500; CA-MA activity against leukemia cells PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0084713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Burkholderia pseudomallei
20 μM
Crystal violet assay
RECORD: Rec_0103617 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
Jurkat
30 μM
IC50
PMID10675500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10675500/
RECORD: Rec_0116880 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antimicrobial Antibacterial Antifungal
Calu-6
10 μM
Concentration response
PaperPeptides with increased + charge and hydrophobicity by substituting one or more amino acids of CA-MA peptide and pharmaceutical compositions containing thereof Evidence URLhttps://patents.google.com/patent/US6800727B2/en PatentUS6800727B2
RECORD: Rec_0122084 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 11009597 PMID11009597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11009597/
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7