Peptide Database

Peptide NameAcidocin A (Bacteriocin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC299H481N83O75S2

DescriptionStandard

        KTYYGTNGVHCTKKSLWGKVRLKNVIPGTLCRKQSLPIKQDLKILLGWATGAFGKTFH
    

Molecular Weight6502.66 Da

Isoelectric Point (pI)10.26

Net Charge (pH 7.0)9.90

Net Charge (pH 7.4) 9.55

Charge Density (pH 7.0) 0.1708

GRAVY Index-0.30

Hydrophobic Moment 0.41

Boman Index0.01

Instability Index23.98

Aliphatic Index 85.69

Aromaticity 0.1034

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2563.32

LogP -21.73

H-bond Donors 93.0

H-bond Acceptors 89.0

Rotatable Bonds 218.0

Heavy Atoms 459.0

Ring Count 12.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204488 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus acidophilus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStreptococcus thermophilus

MethodDirect growth inhibition assay (qualitative spectrum)

PaperKanatani K, Oshimura M, Sano K. Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus. Appl Environ Microbiol. 1995;61(3):1061-1067. doi:10.1128/AEM.61.3.1061-1067.1995. PMID:7793908. PMID7793908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11254635/

RECORD: Rec_0232919 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus acidophilus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetLactococcus lactis

MethodDirect growth inhibition assay (qualitative spectrum)

PaperKanatani K, Oshimura M, Sano K. Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus. Appl Environ Microbiol. 1995;61(3):1061-1067. doi:10.1128/AEM.61.3.1061-1067.1995. PMID:7793908. PMID7793908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11254635/

RECORD: Rec_0270783 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus acidophilus [Bacterium]

FamilyBacteriocin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetListeria monocytogenes

MethodDirect growth inhibition assay (qualitative spectrum)

PaperKanatani K, Oshimura M, Sano K. Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus. Appl Environ Microbiol. 1995;61(3):1061-1067. doi:10.1128/AEM.61.3.1061-1067.1995. PMID:7793908. PMID7793908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7793908/

RECORD: Rec_0278318 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus acidophilus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetEnterococcus faecalis

MethodDirect growth inhibition assay (qualitative spectrum)

PaperKanatani K, Oshimura M, Sano K. Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus. Appl Environ Microbiol. 1995;61(3):1061-1067. doi:10.1128/AEM.61.3.1061-1067.1995. PMID:7793908. PMID7793908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11254635/

RECORD: Rec_0343679 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus acidophilus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetLactobacillus casei

MethodDirect growth inhibition assay (qualitative spectrum)

PaperKanatani K, Oshimura M, Sano K. Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus. Appl Environ Microbiol. 1995;61(3):1061-1067. doi:10.1128/AEM.61.3.1061-1067.1995. PMID:7793908. PMID7793908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11254635/

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