Peptide Database

Peptide NameTPA: neutrophil beta-defensin 12-like [Bos taurus].

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC309H508N94O75S8

DescriptionStandard

        MRLHHLLLALLFLVLSAASGFTQGISGPLSCGRNGGVCIPIRCPVPMRQIGTCFRRPVKCCRSW
    

Molecular Weight6996.44 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.21

Charge Density (pH 7.0) 0.1190

GRAVY Index0.50

Hydrophobic Moment 0.80

Boman Index0.14

Instability Index42.05

Aliphatic Index 102.03

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2656.02

LogP -24.26

H-bond Donors 101.0

H-bond Acceptors 93.0

Rotatable Bonds 223.0

Heavy Atoms 486.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140123 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial