Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length440 amino acids

Chemical FormulaC2183H3505N575O619S20

DescriptionStandard

        MKSCSLSIVLLVSTLSSISATDQTGLKIRITDRALDVLKDFGLKALKQLVNKQFPDFSLLCGCNMCRIKGFTLTNLTVDPEQVVLGFQEKSGLQLEIRDLYFTGKLEQELPVYWFQEFMHTGTVAFEGKDVSATIGLKLRRTQRGRLRVEIPTCEVRAEFGATASGRVVGPVWDLLRFLIHDFINTKLCSTVQMTLVNIVNFMLDDVSMQLHKVLNMSFLSRIVPDVSVDLSLSADVSVSSCSLDLPLRGLVWQGVAVDVGAVPVGPDPVFSEAKKMAYVGISELFFNSAASLAHRLGPFQLSIPEGPVEVNLTQAPVVSISQSGLCVDLKATAWSLRDAPGAPVAADCRLQLKVELKGNRLTLVIQSSKCNIQPETLKGRVMKPIVNYFIKCKTKGFLKSWFDEGLPIPLPEGLHFTRGKIVYHTGFLVVGGNLDFTPN
    

Molecular Weight48350.96 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)4.96

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0113

GRAVY Index0.21

Hydrophobic Moment 0.78

Boman Index0.13

Instability Index26.59

Aliphatic Index 105.57

Aromaticity 0.0773

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152134 VERIFIED: NO

Provenance & Taxonomy

OrganismBetta splendens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria