Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC839H1347N251O248S12

DescriptionStandard

        MANLKTKLSSAMLALIAAGASAPVLMDQFLNEKEGKSLTSYRDGAGIWTICRGVTQVDGRPVTQGMKLTQAKCDQVNAVERNEALAWVDQNVRVRLTPPQKVGIASFCPYNIGPGKCFPSTFYRKLNAGARKGACAEIRRWIFDGGKDCRVRPNNCYGQVSRRDQESALACWGIDE
    

Molecular Weight19302.98 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.06

Charge Density (pH 7.0) 0.0480

GRAVY Index-0.33

Hydrophobic Moment 0.71

Boman Index-0.05

Instability Index32.56

Aliphatic Index 74.89

Aromaticity 0.0739

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8098.73

LogP -91.13

H-bond Donors 289.0

H-bond Acceptors 269.0

Rotatable Bonds 642.0

Heavy Atoms 1350.0

Ring Count 25.0

Amide Bonds 193.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0279000 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence