Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC506H827N129O136S4

DescriptionStandard

        MNHSVKLKAANLGFLLALGIVLLSTYAFLLGMLPEMNLVKEFNIPTSVASAALGYLDVISNAVALAGAIAALGTGGASLIAAAGAQGVKVFLKTMWREKGRKATIAY
    

Molecular Weight11022.02 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.30

Charge Density (pH 7.0) 0.0429

GRAVY Index0.79

Hydrophobic Moment 0.62

Boman Index0.34

Instability Index9.41

Aliphatic Index 124.21

Aromaticity 0.0748

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4171.71

LogP -33.03

H-bond Donors 145.0

H-bond Acceptors 146.0

Rotatable Bonds 366.0

Heavy Atoms 775.0

Ring Count 12.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226274 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus VD022 [Bacterium]

FamilyBacteriocin

Tax ID718223

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal