Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC894H1416N248O242S8

DescriptionStandard

        AHEPMLLLAVTEFVANSAAFTYFTSGALRRNISSSMIPRRFPLQLTTKSMGVFSPQLQDRYPDQPMELHLSARRQPLLSCHPDALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLRGTVSLTGPLCLRHAGLRGLPVLQVKSLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight19766.84 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)6.29

Net Charge (pH 7.4) 5.72

Charge Density (pH 7.0) 0.0348

GRAVY Index0.14

Hydrophobic Moment 0.55

Boman Index0.13

Instability Index56.66

Aliphatic Index 97.02

Aromaticity 0.0773

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7681.81

LogP -85.88

H-bond Donors 267.0

H-bond Acceptors 262.0

Rotatable Bonds 623.0

Heavy Atoms 1392.0

Ring Count 39.0

Amide Bonds 193.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363799 VERIFIED: NO

Provenance & Taxonomy

OrganismAramus guarauna (Limpkin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria