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MYP_140742
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Basic Information
Antimicrobial peptide brevinin-2ZHa precursor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
37 amino acids
C169H292N50O45S3
Standard
Sequence
GIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC
Physicochemical Analysis
3840.63 Da
10.32
6.74
6.49
0.1820
0.28
0.79
0.06
-8.84
92.16
0.0541
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1552.15
-16.34
58.0
55.0
136.0
267.0
2.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142299 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
5 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0184506 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0232609 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 2592
1 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0266661 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 2002
3 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
RECORD: Rec_0276459 VERIFIED: YES
Provenance & Taxonomy
Rana zhenhaiensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa ATCC 9027
5 μM
MIC
PMID22943778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22943778/
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